AGER Antibody

• Background :

  AGER encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6.

• NCBI Gene ID :

  177

• Swiss Prot :

  Q15109

• Accession Number :

  Q15109

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This AGER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human AGER.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  43 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  AGER

• NCBI Official Name :

  Advanced glycosylation end product-specific receptor

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rojas, A., et al. Carcinogenesis 31 (3) :334-341 (2010)

• Background Reference 02 :

  Engelen, L., et al. J. Hypertens. 28 (2) :285-293 (2010)

• Background Reference 03 :

  Poon, P.Y., et al. Clin. Nephrol. 73 (1) :44-50 (2010)

• Background Reference 04 :

  Hancock, D.B., et al. Nat. Genet. 42 (1) :45-52 (2010)

• Other Product Names :

  Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, RAGE

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  2497317

• Physical Properties :

  Liquid