U2AF1 Antibody

• Background:

  U2AF1 belongs to the splicing factor SR family. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers.

• NCBI Gene ID:

  1027245947307

• Swiss Prot:

  Q01081

• Accession Number:

  Q01081

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This U2AF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human U2AF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  U2AF1

• NCBI Official Name:

  Splicing factor U2AF 35 kDa subunit

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rino, J., Mol. Cell. Biol. 28 (9), 3045-3057 (2008) Little, J.T., J. Biol. Chem. 283 (13), 8145-8152 (2008) Pacheco, T.R., Mol. Cell. Biol. 26 (21), 8183-8190 (2006)

• Other Product Names:

  Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit, U2AF1, U2AF35, U2AFBP

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  267187

• Physical Properties:

  Liquid