LGR5 Antibody

• Background:

  LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.

• NCBI Gene ID:

  8549

• Swiss Prot:

  O75473

• Accession Number:

  O75473

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LGR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-638 amino acids from human LGR5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction, Growth Factors

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  100 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  LGR5

• NCBI Official Name:

  Leucine-rich repeat-containing G-protein coupled receptor 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Barker, N., Nature 449 (7165), 1003-1007 (2007) McClanahan, T., Cancer Biol. Ther. (4), 419-426 (2006) Yamamoto, Y., Hepatology 37 (3), 528-533 (2003) Hsu, S.Y., Mol. Endocrinol. 14 (8), 1257-1271 (2000)

• Other Product Names:

  Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, LGR5, GPR49, GPR67

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid