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Junctophilin 3 Antibody

CAT: 0223-61-445Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-445Size:400 µL
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Background
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.
NCBI Gene ID
57340
Swiss Prot
Q9ET77
Accession Number
Q9ET77
Host
Rabbit
Reactivity
Mouse
Immunogen
This Junctophilin 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human Junctophilin 3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Human
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
81 kDa
Fragment
Rabbit Ig
Symbol
Jph3
NCBI Official Name
Junctophilin-3
NCBI Organism
Mus musculus
Background Reference 01
Kakizawa, S., EMBO J. 26 (7), 1924-1933 (2007)
Background Reference 02
Moriguchi, S., Proc. Natl. Acad. Sci. U.S.A. 103 (28), 10811-10816 (2006)
Background Reference 03
Nishi, M., Brain Res. Mol. Brain Res. 118 (1-2), 102-110 (2003)
Background Reference 04
Nishi, M., Biochem. Biophys. Res. Commun. 292 (2), 318-324 (2002)
Other Product Names
Junctophilin-3, JP-3, Junctophilin type 3, Jph3, Jp3
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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