Junctophilin 3 Antibody

• Background:

  Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.

• NCBI Gene ID:

  57340

• Swiss Prot:

  Q9ET77

• Accession Number:

  Q9ET77

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Junctophilin 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human Junctophilin 3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein G column, followed by dialysis against PBS.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Human

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  81 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Jph3

• NCBI Official Name:

  Junctophilin-3

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Kakizawa, S., EMBO J. 26 (7), 1924-1933 (2007)

• Background Reference 02:

  Moriguchi, S., Proc. Natl. Acad. Sci. U.S.A. 103 (28), 10811-10816 (2006)

• Background Reference 03:

  Nishi, M., Brain Res. Mol. Brain Res. 118 (1-2), 102-110 (2003)

• Background Reference 04:

  Nishi, M., Biochem. Biophys. Res. Commun. 292 (2), 318-324 (2002)

• Other Product Names:

  Junctophilin-3, JP-3, Junctophilin type 3, Jph3, Jp3

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid