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ACOX1 Antibody

CAT: 0223-61-412Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-412Size:400 µL
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Background
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.
NCBI Gene ID
51
Swiss Prot
Q15067
Accession Number
Q15067
Host
Rabbit
Reactivity
Human
Immunogen
This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-659 amino acids from the C-terminal region of human ACOX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ACOX1
NCBI Official Name
Peroxisomal acyl-coenzyme A oxidase 1
NCBI Organism
Homo sapiens
Background Reference 01
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .
Background Reference 02
Chu, R., et al., J. Biol. Chem. 270 (9) :4908-4915 (1995) .
Background Reference 03
Aoyama, T., et al., Biochem. Biophys. Res. Commun. 198 (3) :1113-1118 (1994) .
Background Reference 04
Fournier, B., et al., J. Clin. Invest. 94 (2) :526-531 (1994) .
Other Product Names
Peroxisomal acyl-coenzyme A oxidase 1, AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase, SCOX, ACOX1, ACOX
Tested Applications
WB
Protein ID
126302511
Physical Properties
Liquid

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