NMT2 Antibody

• Background:

  N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.

• NCBI Gene ID:

  9397

• Swiss Prot:

  O60551

• Accession Number:

  O60551

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human NMT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NMT2

• NCBI Official Name:

  Glycylpeptide N-tetradecanoyltransferase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lindwasser, O.W., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (20) :13037-13042 (2002) .

• Background Reference 02:

  Kolluri, S.K., et al., Cancer Res. 61 (23) :8534-8539 (2001) .

• Background Reference 03:

  Shiraishi, T., et al., Biochem. Biophys. Res. Commun. 282 (5) :1201-1205 (2001) .

• Background Reference 04:

  Ono, A., et al., J. Virol. 73 (5) :4136-4144 (1999) .

• Other Product Names:

  Glycylpeptide N-tetradecanoyltransferase 2, Myristoyl-CoA:protein N-myristoyltransferase 2, NMT 2, Peptide N-myristoyltransferase 2, Type II N-myristoyltransferase, NMT2

• Tested Applications:

  WB

• Physical Properties:

  Liquid