RAGE Antibody

• Background:

  This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6.

• NCBI Gene ID:

  177

• Swiss Prot:

  Q15109

• Accession Number:

  Q15109

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RAGE (AGER) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-378 amino acids from the C-terminal region of human RAGE (AGER) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  AGER

• NCBI Official Name:

  Advanced glycosylation end product-specific receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Schlueter, C., et al., Biochim. Biophys. Acta 1630 (1) :1-6 (2003) .

• Background Reference 02:

  Shanmugam, N., et al., J. Biol. Chem. 278 (37) :34834-34844 (2003) .

• Background Reference 03:

  Kuniyasu, H., et al., Oncol. Rep. 10 (2) :445-448 (2003) .

• Background Reference 04:

  Hsieh, H.L., et al., Biochem. Biophys. Res. Commun. 307 (2) :375-381 (2003) .

• Other Product Names:

  Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, RAGE

• Tested Applications:

  WB, IHC-P

• Protein ID:

  2497317

• Physical Properties:

  Liquid