PLCB3 Antibody

• Background :

  The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

• NCBI Gene ID :

  5331

• Swiss Prot :

  Q01970

• Accession Number :

  Q01970

• Host :

  Rabbit

• Reactivity :

  Mouse, Rat

• Immunogen :

  This PLCB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from human PLCB3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  139 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:2000

• Symbol :

  PLCB3

• NCBI Official Name :

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Mazuruk K., et al.Biochem. Biophys. Res. Commun. 212:190-195 (1995) .

• Background Reference 02 :

  Lagercrantz J., et al.Genomics 26:467-472 (1995) .

• Background Reference 03 :

  Taylor T.D., et al.Nature 440:497-500 (2006) .

• Background Reference 04 :

  Mural R.J., et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

• Other Product Names :

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, 3.1.4.11, Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3, PLCB3

• Tested Applications :

  WB

• Protein ID :

  1730573

• Physical Properties :

  Liquid