PLCB3 Antibody

• Background:

  The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

• NCBI Gene ID:

  5331

• Swiss Prot:

  Q01970

• Accession Number:

  Q01970

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  This PLCB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from human PLCB3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  139 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  PLCB3

• NCBI Official Name:

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mazuruk K., et al.Biochem. Biophys. Res. Commun. 212:190-195 (1995) .

• Background Reference 02:

  Lagercrantz J., et al.Genomics 26:467-472 (1995) .

• Background Reference 03:

  Taylor T.D., et al.Nature 440:497-500 (2006) .

• Background Reference 04:

  Mural R.J., et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

• Other Product Names:

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, 3.1.4.11, Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3, PLCB3

• Tested Applications:

  WB

• Protein ID:

  1730573

• Physical Properties:

  Liquid