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SH3PXD2B Antibody

CAT: 0223-61-293Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-293Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity) .
NCBI Gene ID
285590
Swiss Prot
A1X283
Accession Number
A1X283
Host
Rabbit
Reactivity
Human
Immunogen
This SH3PXD2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 596-628 amino acids from human SH3PXD2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
102 kDa
Fragment
Rabbit Ig
Symbol
SH3PXD2B
NCBI Official Name
SH3 and PX domain-containing protein 2B
NCBI Organism
Homo sapiens
Background Reference 01
Hishida T., et al.FEBS J. 275:5576-5588 (2008) .
Background Reference 02
Lanyi A., et al.Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Background Reference 03
Schmutz J., et al.Nature 431:268-274 (2004) .
Background Reference 04
Nagase T., et al.DNA Res. 7:65-73 (2000) .
Other Product Names
SH3 and PX domain-containing protein 2B, Adapter protein HOFI, Factor for adipocyte differentiation 49, Tyrosine kinase substrate with four SH3 domains, SH3PXD2B, FAD49, KIAA1295, TKS4
Tested Applications
WB, Flow
Physical Properties
Liquid

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