Products for Research Use Only
RegisterLogin

LRPPRC Antibody

CAT: 0223-61-290Size: 200 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-61-290Size:200 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly (A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly (A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity) .
NCBI Gene ID
10128
Swiss Prot
P42704
Accession Number
P42704
Host
Rabbit
Reactivity
Human
Immunogen
This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1203-1236 amino acids from human LRPPRC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
158 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
LRPPRC
NCBI Official Name
Leucine-rich PPR motif-containing protein, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Xu F., et al.Biochem. J. 382:331-336 (2004) .
Background Reference 02
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 03
Hillier L.W., et al.Nature 434:724-731 (2005) .
Background Reference 04
Hou J., et al.In Vitro Cell. Dev. Biol. Anim. 30A:111-114 (1994) .
Other Product Names
Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130
Tested Applications
WB
Protein ID
156632706
Physical Properties
Liquid

Related Products

CatalogName
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody
15-580POMGNT2 Antibody
5217-01mgPNAS4 Antibody

Alternative Products

CatalogName
FNab04850LRPPRC antibody

Popular Products