THRA Antibody

• Background:

  Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.

• NCBI Gene ID:

  7067

• Swiss Prot:

  P10827

• Accession Number:

  P10827

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  This THRA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 107-139 amino acids from human THRA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Pig, Sheep

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  THRA

• NCBI Official Name:

  Thyroid hormone receptor alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Laudet V., et al.Nucleic Acids Res. 19:1105-1112 (1991) .

• Background Reference 02:

  Miyajima N., et al.Cell 57:31-39 (1989) .

• Background Reference 03:

  Nakai A., et al.Proc. Natl. Acad. Sci. U.S.A. 85:2781-2785 (1988) .

• Background Reference 04:

  Pfahl M., et al.Nucleic Acids Res. 15:9613-9613 (1987) .

• Other Product Names:

  Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha, THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2

• Tested Applications:

  WB

• Protein ID:

  135705

• Physical Properties:

  Liquid