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F7 Antibody

CAT: 0223-61-240Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-240Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
NCBI Gene ID
2155
Swiss Prot
P08709
Accession Number
P08709
Host
Rabbit
Reactivity
Human
Immunogen
This F7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 302-332 amino acids from human F7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
F7
NCBI Official Name
Coagulation factor VII
NCBI Organism
Homo sapiens
Background Reference 01
Hagen F.S., et al.Proc. Natl. Acad. Sci. U.S.A. 83:2412-2416 (1986) .
Background Reference 02
O'Hara P.J., et al.Proc. Natl. Acad. Sci. U.S.A. 84:5158-5162 (1987) .
Background Reference 03
Sabater-Lleal M., et al.Hum. Genet. 118:741-751 (2006) .
Background Reference 04
Soria J.M., et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Other Product Names
Coagulation factor VII, 3.4.21.21, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfa, Factor VII light chain, Factor VII heavy chain, F7
Tested Applications
WB
Protein ID
119766
Physical Properties
Liquid

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