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MGAT4B Antibody

CAT: 0223-61-230Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-230Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.
NCBI Gene ID
11282
Swiss Prot
Q9UQ53
Accession Number
Q9UQ53
Host
Rabbit
Reactivity
Human
Immunogen
This MGAT4B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-62 amino acids from human MGAT4B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
MGAT4B
NCBI Official Name
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
NCBI Organism
Homo sapiens
Background Reference 01
Yoshida A., et al.Glycoconj. J. 15:1115-1123 (1998) .
Background Reference 02
Clark H.F., et al.Genome Res. 13:2265-2270 (2003) .
Background Reference 03
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 04
Schmutz J., et al.Nature 431:268-274 (2004) .
Other Product Names
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B, 2.4.1.145, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, GnT-IVb, N-acetylglucosaminyltransferase IVb, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb, MGAT4B
Tested Applications
WB
Protein ID
74735195
Physical Properties
Liquid

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