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UBE2L3 Antibody

CAT: 0223-61-080Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-080Size:400 µL
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
NCBI Gene ID
7332
Swiss Prot
P68036
Accession Number
P68036
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
18 kDa
Fragment
Rabbit Ig
Symbol
UBE2L3
NCBI Official Name
Ubiquitin-conjugating enzyme E2 L3
NCBI Organism
Homo sapiens
Background Reference 01
Moynihan, T.P., et al., Genomics 51 (1) :124-127 (1998) .
Background Reference 02
Moynihan, T.P., et al., Mamm. Genome 7 (7) :520-525 (1996) .
Background Reference 03
Nuber, U., et al., J. Biol. Chem. 271 (5) :2795-2800 (1996) .
Background Reference 04
Robinson, P.A., et al., Mamm. Genome 6 (10) :725-731 (1995) .
Other Product Names
Ubiquitin-conjugating enzyme E2 L3, L-UBC, UbcH7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3, UBE2L3, UBCE7, UBCH7
Tested Applications
WB, IHC-P
Protein ID
54039805
Physical Properties
Liquid

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