UBE2L6 Antibody

• Background:

  The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

• NCBI Gene ID:

  9246

• Swiss Prot:

  O14933

• Accession Number:

  O14933

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  18 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  UBE2L6

• NCBI Official Name:

  Ubiquitin/ISG15-conjugating enzyme E2 L6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kumar, S., et al., J. Biol. Chem. 272 (21) :13548-13554 (1997) . Ardley, H.C., et al., Cytogenet. Cell Genet. 89 (1-2), 137-140 (2000) .

• Other Product Names:

  Ubiquitin/ISG15-conjugating enzyme E2 L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBE2L6, UBCH8

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid