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FXR1 Antibody

CAT: 0223-60-914Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-914Size:400 µL
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Background
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8087
Swiss Prot
P51114
Accession Number
P51114
Host
Rabbit
Reactivity
Mouse
Immunogen
This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FXR1
NCBI Official Name
Fragile X mental retardation syndrome-related protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Coffee, R.L. Jr., et al. Dis Model Mech (7-8), 471-485 (2010) :
Background Reference 02
Darnell, J.C., et al. Hum. Mol. Genet. 18 (17) :3164-3177 (2009)
Background Reference 03
Purcell, S.M., et al. Nature 460 (7256) :748-752 (2009)
Background Reference 04
Davidovic, L., et al. J. Med. Genet. 45 (10) :679-685 (2008)
Other Product Names
Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Tested Applications
WB
Protein ID
189047132
Physical Properties
Liquid

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