GLUD2 Antibody

• Background:

  The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

• NCBI Gene ID:

  2747

• Swiss Prot:

  P49448

• Accession Number:

  P49448

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GLUD2

• NCBI Official Name:

  Glutamate dehydrogenase 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Spanaki, C., et al. J. Biol. Chem. 285 (22) :16748-16756 (2010)

• Background Reference 02:

  Plaitakis, A., et al. Eur. J. Hum. Genet. 18 (3) :336-341 (2010)

• Background Reference 03:

  Zaganas, I., et al. Neurochem. Int. 55 (1-3), 52-63 (2009) :

• Background Reference 04:

  Mastorodemos, V., et al. Biochem. Cell Biol. 87 (3) :505-516 (2009)

• Other Product Names:

  Glutamate dehydrogenase 2, mitochondrial, GDH 2, GLUD2, GLUDP1

• Tested Applications:

  WB

• Protein ID:

  13432152

• Physical Properties:

  Liquid