CHRNB4 Antibody

• Background:

  After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

• NCBI Gene ID:

  1143

• Swiss Prot:

  P30926

• Accession Number:

  P30926

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CHRNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human CHRNB4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CHRNB4

• NCBI Official Name:

  Neuronal acetylcholine receptor subunit beta-4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, H., et al. Neuropsychopharmacology 35 (11) :2211-2224 (2010)

• Background Reference 02:

  Saccone, N.L., et al. Genes Brain Behav. 9 (7) :741-750 (2010)

• Background Reference 03:

  Hansen, H.M., et al. Hum. Mol. Genet. 19 (18) :3652-3661 (2010)

• Background Reference 04:

  Amos, C.I., et al. J. Natl. Cancer Inst. 102 (15) :1199-1205 (2010)

• Other Product Names:

  Neuronal acetylcholine receptor subunit beta-4, CHRNB4

• Tested Applications:

  WB

• Protein ID:

  2506129

• Physical Properties:

  Liquid