CHRNB4 Antibody

• Background :

  After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

• NCBI Gene ID :

  1143

• Swiss Prot :

  P30926

• Accession Number :

  P30926

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CHRNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human CHRNB4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  56 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  CHRNB4

• NCBI Official Name :

  Neuronal acetylcholine receptor subunit beta-4

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Zhang, H., et al. Neuropsychopharmacology 35 (11) :2211-2224 (2010)

• Background Reference 02 :

  Saccone, N.L., et al. Genes Brain Behav. 9 (7) :741-750 (2010)

• Background Reference 03 :

  Hansen, H.M., et al. Hum. Mol. Genet. 19 (18) :3652-3661 (2010)

• Background Reference 04 :

  Amos, C.I., et al. J. Natl. Cancer Inst. 102 (15) :1199-1205 (2010)

• Other Product Names :

  Neuronal acetylcholine receptor subunit beta-4, CHRNB4

• Tested Applications :

  WB

• Protein ID :

  2506129

• Physical Properties :

  Liquid