CHRNB2 Antibody

• Background:

  The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Mutations in neuronal nicotinic acetylcholine receptor beta 2 subunit have been associated with autosomal dominant nocturnal frontal lobe epilepsies.

• NCBI Gene ID:

  1141

• Swiss Prot:

  P17787

• Accession Number:

  NP_000739

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNB2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHRNB2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  57 kDa

• Applications Notes:

  CHRNB2 antibody can be used for detection of CHRNB2 by ELISA at 1:62500. CHRNB2 antibody can be used for detection of CHRNB2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CHRNB2

• NCBI Official Name:

  Cholinergic receptor, nicotinic, beta 2 (neuronal)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hales, T.G., et al., (2006) J. Biol. Chem. 281 (12), 8062-8071.

• Other Product Names:

  CHRNB2, EFNL3, nAChRB2

• Tested Applications:

  ELISA, WB

• Protein ID:

  4502833

• Physical Properties:

  Liquid