CHRNB2 Antibody

• Background:

  Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.

• NCBI Gene ID:

  1141

• Swiss Prot:

  P17787

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 340-430 of human CHRNB2 (NP_000739.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50-52kDa

• Fragment:

  IgG

• Symbol:

  CHRNB2

• Positive Control 2:

  SH-SY5Y

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  Cholinergic receptor, nicotinic, beta 2 (neuronal)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CHRNB2, EFNL3, nAChRB2

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid