HPS5 Antibody

• Background:

  This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

• NCBI Gene ID:

  11234

• Swiss Prot:

  Q9UPZ3

• Accession Number:

  Q9UPZ3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  127 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  HPS5

• NCBI Official Name:

  Hermansky-Pudlak syndrome 5 protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Helip-Wooley, A., et al. J. Invest. Dermatol. 127 (6) :1471-1478 (2007)

• Background Reference 02:

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Background Reference 03:

  Huizing, M., et al. Platelets 18 (2) :150-157 (2007)

• Background Reference 04:

  Huizing, M., et al. Traffic 5 (9) :711-722 (2004)

• Other Product Names:

  Hermansky-Pudlak syndrome 5 protein, Alpha-integrin-binding protein 63, Ruby-eye protein 2 homolog, Ru2, HPS5, AIBP63, KIAA1017

• Tested Applications:

  WB

• Protein ID:

  29429222

• Physical Properties:

  Liquid