HPS5 Antibody

CAT: 0223-60-837Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-837Size:400 µL
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Background
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
NCBI Gene ID
11234
Swiss Prot
Q9UPZ3
Accession Number
Q9UPZ3
Host
Rabbit
Reactivity
Human
Immunogen
This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
127 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HPS5
NCBI Official Name
Hermansky-Pudlak syndrome 5 protein
NCBI Organism
Homo sapiens
Background Reference 01
Helip-Wooley, A., et al. J. Invest. Dermatol. 127 (6) :1471-1478 (2007)
Background Reference 02
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Background Reference 03
Huizing, M., et al. Platelets 18 (2) :150-157 (2007)
Background Reference 04
Huizing, M., et al. Traffic 5 (9) :711-722 (2004)
Other Product Names
Hermansky-Pudlak syndrome 5 protein, Alpha-integrin-binding protein 63, Ruby-eye protein 2 homolog, Ru2, HPS5, AIBP63, KIAA1017
Tested Applications
WB
Protein ID
29429222
Physical Properties
Liquid

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