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HPS3 Antibody

CAT: 0223-58-778Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-778Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. [provided by RefSeq].
NCBI Gene ID
84343
Swiss Prot
Q969F9
Accession Number
Q969F9
Host
Rabbit
Reactivity
Human
Immunogen
This HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the N-terminal region of human HPS3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
114 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HPS3
NCBI Official Name
Hermansky-Pudlak syndrome 3 protein
NCBI Organism
Homo sapiens
Background Reference 01
Torres-Serrant, M., et al. J. Pediatr. Hematol. Oncol. 32 (6) :448-453 (2010)
Background Reference 02
Huizing, M., et al. Platelets 18 (2) :150-157 (2007)
Background Reference 03
Santiago Borrero, P.J., et al. J. Invest. Dermatol. 126 (1) :85-90 (2006)
Background Reference 04
Boissy, R.E., et al. Am. J. Pathol. 166 (1) :231-240 (2005)
Other Product Names
Hermansky-Pudlak syndrome 3 protein, HPS3
Tested Applications
WB
Protein ID
20532121
Physical Properties
Liquid

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