ATP6AP2 Antibody

• Background:

  This gene encodes a protein that is associated with adenosine triphosphatases (ATPases) . Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

• NCBI Gene ID:

  10159

• Swiss Prot:

  O75787

• Accession Number:

  O75787

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ATP6AP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human ATP6AP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ATP6AP2

• NCBI Official Name:

  Renin receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Takahashi, K., et al. Peptides 31 (7) :1405-1408 (2010)

• Background Reference 02:

  Cruciat, C.M., et al. Science 327 (5964) :459-463 (2010)

• Background Reference 03:

  Nabi, A.H., et al. Biochim. Biophys. Acta 1794 (12) :1838-1847 (2009)

• Background Reference 04:

  Alcazar, O., et al. Exp. Eye Res. 89 (5) :638-647 (2009)

• Other Product Names:

  Renin receptor, ATPase H (+) -transporting lysosomal accessory protein 2, ATPase H (+) -transporting lysosomal-interacting protein 2, ER-localized type I transmembrane adaptor, Embryonic liver differentiation factor 10, N14F, Renin/prorenin receptor, Vacuolar ATP synthase membrane sector-associated protein M8-9, ATP6M8-9, V-ATPase M89 subunit, ATP6AP2, ATP6IP2, CAPER, ELDF10

• Tested Applications:

  WB

• Physical Properties:

  Liquid