Products for Research Use Only

NLN Antibody

CAT: 0223-60-788Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-788Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin (1-10) and neurotensin (11-13) . The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
NCBI Gene ID
57486
Swiss Prot
Q9BYT8
Accession Number
Q9BYT8
Host
Rabbit
Reactivity
Human
Immunogen
This NLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of human NLN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
81 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NLN
NCBI Official Name
Neurolysin, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 02
Lim, E.J., et al. J. Biol. Chem. 282 (13) :9722-9732 (2007)
Background Reference 03
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Background Reference 04
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Other Product Names
Neurolysin, mitochondrial, Angiotensin-binding protein, Microsomal endopeptidase, MEP, Mitochondrial oligopeptidase M, Neurotensin endopeptidase, NLN, AGTBP, KIAA1226
Tested Applications
WB
Protein ID
20139130
Physical Properties
Liquid