AMPH Antibody

• Background:

  This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

• NCBI Gene ID:

  273

• Swiss Prot:

  P49418

• Accession Number:

  P49418

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This AMPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human AMPH.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  76 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  AMPH

• NCBI Official Name:

  Amphiphysin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  He, P., et al. Amino Acids 38 (4) :1209-1218 (2010)

• Background Reference 02:

  Liu, L., et al. Protein Pept. Lett. 17 (2) :246-253 (2010)

• Background Reference 03:

  Hou, T., et al. J. Mol. Biol. 376 (4) :1201-1214 (2008)

• Background Reference 04:

  Zhou, P., et al. Biopolymers 90 (6) :792-802 (2008)

• Other Product Names:

  Amphiphysin, AMPH, AMPH1

• Tested Applications:

  WB

• Protein ID:

  1351924

• Physical Properties:

  Liquid