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NDUFS6 Antibody

CAT: 0223-60-731Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-731Size:400 µL
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Background
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
NCBI Gene ID
4726
Swiss Prot
O75380
Accession Number
O75380
Host
Rabbit
Reactivity
Human
Immunogen
This NDUFS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human NDUFS6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NDUFS6
NCBI Official Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Saito, A., et al. J. Hum. Genet. 54 (6) :317-323 (2009)
Background Reference 02
Martins-de-Souza, D., et al.Neural Transm 116 (3) :275-289 (2009)
Background Reference 03
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008)
Background Reference 04
Starr, J.M., et al. Mech. Ageing Dev. 129 (12) :745-751 (2008)
Other Product Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial, Complex I-13kD-A, CI-13kD-A, NADH-ubiquinone oxidoreductase 13 kDa-A subunit, NDUFS6
Tested Applications
WB
Physical Properties
Liquid

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