NDUFS8 Antibody

• Background:

  This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

• NCBI Gene ID:

  4728

• Swiss Prot:

  O00217

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 35-210 of human NDUFS8 (NP_002487.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 23kDa

• Fragment:

  IgG

• Symbol:

  NDUFS8

• Positive Control 2:

  Mouse heart

• Positive Control 3:

  Mouse kidney

• NCBI Official Name:

  NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NDUFS8, TYKY, NADH-ubiquinone oxidoreductase 23 kDa subunit, NADH dehydrogenase ubiquinone Fe-S 8, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase), complex I-23kD, CI23KD, CI-23k

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid