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NDUFS2 Antibody

CAT: 0223-64-103Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-103Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NDUFS2 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) . Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria.
NCBI Gene ID
4720
Swiss Prot
O75306
Accession Number
O75306
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This NDUFS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human NDUFS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
NDUFS2
NCBI Official Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Saada, A., et al. Am. J. Hum. Genet. 84 (6) :718-727 (2009) Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008) Starr, J.M., et al. Mech. Ageing Dev. 129 (12) :745-751 (2008) Ban, M., et al. PLoS ONE (8), E2891 (2008) Triepels, R.H., et al. J. Biol. Chem. 276 (12) :8892-8897 (2001)
Other Product Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit, NDUFS2
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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