KRT7 Antibody

• Background:

  The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.

• NCBI Gene ID:

  3855

• Swiss Prot:

  P08729

• Accession Number:

  P08729

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KRT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human KRT7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KRT7

• NCBI Official Name:

  Keratin, type II cytoskeletal 7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tsai, Y.Y., et al. Acta Derm. Venereol. 90 (4) :438-439 (2010)

• Background Reference 02:

  Stewart, C.J., et al. Histopathology 57 (1) :46-54 (2010)

• Background Reference 03:

  Nagashio, R., et al. Pathol. Int. 60 (2) :71-77 (2010)

• Background Reference 04:

  Sano, M., et al. Int. J. Oncol. 36 (2) :321-330 (2010)

• Other Product Names:

  Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL

• Tested Applications:

  WB, IHC-P

• Protein ID:

  317373583

• Physical Properties:

  Liquid