ASTN2 Antibody

• Background:

  This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus.

• NCBI Gene ID:

  23245

• Swiss Prot:

  O75129

• Accession Number:

  O75129

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This ASTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the N-terminal region of human ASTN2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  148 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ASTN2

• NCBI Official Name:

  Astrotactin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Adkins, D.E., et al. Mol. Psychiatry (2010) In press :

• Background Reference 03:

  Lesch, K.P., et al.Neural Transm 115 (11) :1573-1585 (2008)

• Background Reference 04:

  Vrijenhoek, T., et al. Am. J. Hum. Genet. 83 (4) :504-510 (2008)

• Other Product Names:

  Astrotactin-2, ASTN2, KIAA0634

• Tested Applications:

  WB

• Physical Properties:

  Liquid