PRPS1L1 Antibody

• Background:

  This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq].

• NCBI Gene ID:

  221823

• Swiss Prot:

  P21108

• Accession Number:

  P21108

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PRPS1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human PRPS1L1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PRPS1L1

• NCBI Official Name:

  Ribose-phosphate pyrophosphokinase 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Venter, J.C., et al. Science 291 (5507) :1304-1351 (2001)

• Background Reference 02:

  Taira, M., et al. J. Biol. Chem. 265 (27) :16491-16497 (1990)

• Other Product Names:

  Ribose-phosphate pyrophosphokinase 3, Phosphoribosyl pyrophosphate synthase 1-like 1, PRPS1-like 1, Phosphoribosyl pyrophosphate synthase III, PRS-III, PRPS1L1, PRPS3, PRPSL

• Tested Applications:

  WB

• Protein ID:

  125585

• Physical Properties:

  Liquid