PRPS1 Antibody

• Background:

  This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5631

• Swiss Prot:

  P60891

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human PRPS1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Raji

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 35kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PRPS1

• Positive Control 2:

  U-87MG

• Positive Control 3:

  SW620

• Positive Control 4:

  HT-29

• Positive Control 5:

  Mouse lung

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Ribose-phosphate pyrophosphokinase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1

• Tested Applications:

  WB

• Physical Properties:

  Liquid