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LONP1 Antibody

CAT: 0223-60-602Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-602Size:400 µL
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Background
This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.
NCBI Gene ID
9361
Swiss Prot
P36776
Accession Number
P36776
Host
Rabbit
Reactivity
Human
Immunogen
This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
106 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LONP1
NCBI Official Name
Lon protease homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03120}
NCBI Organism
Homo sapiens
Background Reference 01
Hansen, J., et al. Neurobiology 153 (2) :474-482 (2008)
Background Reference 02
Chen, S.H., et al. Nucleic Acids Res. 36 (4) :1273-1287 (2008)
Background Reference 03
Bogenhagen, D.F., et al. J. Biol. Chem. 283 (6) :3665-3675 (2008)
Background Reference 04
Bayot, A., et al. Biochimie 90 (2) :260-269 (2008)
Other Product Names
Lon protease homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03120}, 3421- {ECO:0000255|HAMAP-Rule:MF_03120}, LONHs, Lon protease-like protein {ECO:0000255|HAMAP-Rule:MF_03120}, LONP {ECO:0000255|HAMAP-Rule:MF_03120}, Mitochondrial ATP-dependent protease Lon {ECO:0000255|HAMAP-Rule:MF_03120}, Serine protease 15 {ECO:0000255|HAMAP-Rule:MF_03120}, LONP1 {ECO:0000255|HAMAP-Rule:MF_03120}, PRSS15
Tested Applications
WB
Protein ID
12644239
Physical Properties
Liquid

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