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SSH1 Antibody

CAT: 0223-60-530Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-530Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .
NCBI Gene ID
54434
Swiss Prot
Q8WYL5
Accession Number
Q8WYL5
Host
Rabbit
Reactivity
Human
Immunogen
This SSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human SSH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
116 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SSH1
NCBI Official Name
Protein phosphatase Slingshot homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Song, S.Y., et al. APMIS 118 (5) :389-393 (2010)
Background Reference 02
Peterburs, P., et al. Cancer Res. 69 (14) :5634-5638 (2009)
Background Reference 03
Kligys, K., et al. Biochem. Biophys. Res. Commun. 383 (4) :450-454 (2009)
Background Reference 04
Kim, J.S., et al. Mol. Biol. Cell 20 (11) :2650-2660 (2009)
Other Product Names
Protein phosphatase Slingshot homolog 1, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L
Tested Applications
WB
Protein ID
82582267
Physical Properties
Liquid

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