SSH3 Antibody

• Background :

  The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .

• NCBI Gene ID :

  54961

• Swiss Prot :

  Q8TE77

• Accession Number :

  Q8TE77

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SSH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the C-terminal region of human SSH3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  73 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  SSH3

• NCBI Official Name :

  Protein phosphatase Slingshot homolog 3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kousaka, K., et al. Genesis 46 (5) :246-255 (2008)

• Background Reference 02 :

  Kligys, K., et al. J. Biol. Chem. 282 (44) :32520-32528 (2007)

• Background Reference 03 :

  Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

• Background Reference 04 :

  Soosairajah, J., et al. EMBO J. 24 (3) :473-486 (2005)

• Other Product Names :

  Protein phosphatase Slingshot homolog 3, SSH-like protein 3, SSH-3L, hSSH-3L, SSH3, SSH3L

• Tested Applications :

  WB, IHC-P, IF, Flow

• Protein ID :

  82582268

• Physical Properties :

  Liquid