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RALBP1 Antibody

CAT: 0223-60-516Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-516Size:400 µL
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Background
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550) . Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]) .
NCBI Gene ID
10928
Swiss Prot
Q15311
Accession Number
Q15311
Host
Rabbit
Reactivity
Human
Immunogen
This RALBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human RALBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RALBP1
NCBI Official Name
RalA-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Singhal, S.S., et al. Int. J. Cancer 126 (6) :1327-1338 (2010)
Background Reference 02
Singhal, S.S., et al. Cancer Lett. 283 (2) :152-158 (2009)
Background Reference 03
Awasthi, Y.C., et al.Toxicol Environ HealthCrit Rev 12 (7) :540-551 (2009)
Background Reference 04
Singhal, S.S., et al. Cancer Res. 69 (10) :4244-4251 (2009)
Other Product Names
RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76
Tested Applications
WB
Protein ID
34098413
Physical Properties
Liquid

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