RALBP1 Antibody

• Background:

  RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550) . Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]) .

• NCBI Gene ID:

  10928

• Swiss Prot:

  Q15311

• Accession Number:

  Q15311

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RALBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human RALBP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  76 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RALBP1

• NCBI Official Name:

  RalA-binding protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Singhal, S.S., et al. Int. J. Cancer 126 (6) :1327-1338 (2010)

• Background Reference 02:

  Singhal, S.S., et al. Cancer Lett. 283 (2) :152-158 (2009)

• Background Reference 03:

  Awasthi, Y.C., et al.Toxicol Environ HealthCrit Rev 12 (7) :540-551 (2009)

• Background Reference 04:

  Singhal, S.S., et al. Cancer Res. 69 (10) :4244-4251 (2009)

• Other Product Names:

  RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76

• Tested Applications:

  WB

• Protein ID:

  34098413

• Physical Properties:

  Liquid