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NR2F2 Antibody

CAT: 0223-31-192Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-192Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
NCBI Gene ID
7026
Swiss Prot
P24468
Accession Number
NP_066285
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR2F2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
NR2F2 antibody can be used for detection of NR2F2 by ELISA at 1:62500. NR2F2 antibody can be used for detection of NR2F2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR2F2
NCBI Official Name
Nuclear receptor subfamily 2, group F, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Schafer, G., (2008) Cancer Res. 68 (2), 457-466.
Other Product Names
NR2F2, ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII
Tested Applications
ELISA, WB
Protein ID
14149746
Physical Properties
Liquid

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