NR2F2 Antibody

CAT: 0223-29-062Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-062Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
NCBI Gene ID
7026
Swiss Prot
P24468
Accession Number
NP_066285
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR2F2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
NR2F2 antibody can be used for detection of NR2F2 by ELISA at 1:312500. NR2F2 antibody can be used for detection of NR2F2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR2F2
NCBI Official Name
Nuclear receptor subfamily 2, group F, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Sato, Y., (2003) J. Clin. Endocrinol. Metab. 88 (7), 3415-3420.
Other Product Names
NR2F2, ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII
Tested Applications
ELISA, WB, IHC
Protein ID
14149746
Physical Properties
Liquid

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