ITGB1 Antibody

• Background:

  Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

• NCBI Gene ID:

  3688

• Swiss Prot:

  P05556

• Accession Number:

  P05556

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ITGB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-785 amino acids from the C-terminal region of human ITGB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Chicken, Xenopus, Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  88 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ITGB1

• NCBI Official Name:

  Integrin beta-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Martchenko, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15583-15588 (2010) Caicedo-Carvajal, C.E., et al. PLoS ONE (7), E11830 (2010) Rikova, K., et al. Cell 131 (6) :1190-1203 (2007) Seales, E.C., et al. J. Biol. Chem. 280 (45) :37610-37615 (2005) Armulik, A. Front. Biosci. 7, D219-D227 (2002) :

• Other Product Names:

  Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12

• Tested Applications:

  WB

• Protein ID:

  218563324

• Physical Properties:

  Liquid