ITGB1 (phospho Tyr795) Antibody

• Background:

  Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

• NCBI Gene ID:

  3688

• Swiss Prot:

  P05556

• Accession Number:

  NP_002202.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  ITGB1 (phospho Tyr795) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 795 (P-K-Y (p) -E-G) derived from Human ITGB1 .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  140 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of ITGB1 only when phosphorylated at tyrosine 795.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  ITGB1

• NCBI Official Name:

  Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Argraves W.S., J. Cell Biol. 105:1183-1190 (1987) .

• Background Reference 02:

  Ota T., Nat. Genet. 36:40-45 (2004) .

• Background Reference 03:

  Bechtel S., BMC Genomics 8:399-399 (2007) .

• Other Product Names:

  CD29, FNRB, ITB1

• Tested Applications:

  WB

• Protein ID:

  19743813

• Physical Properties:

  Liquid