Reptin/TIP49B/RUVB2 Antibody

• Background:

  This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

• NCBI Gene ID:

  10856

• Swiss Prot:

  Q9Y230

• Accession Number:

  Q9Y230

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Reptin/TIP49B/RUVB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the C-terminal region of human Reptin/TIP49B/RUVB2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Xenopus, Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RUVBL2

• NCBI Official Name:

  RuvB-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bauer, A., et al., EMBO J. 19 (22) :6121-6130 (2000) .

• Background Reference 02:

  Parfait, B., et al., Ann. Genet. 43 (2) :69-74 (2000) .

• Background Reference 03:

  Wood, M.A., et al., Mol. Cell 5 (2) :321-330 (2000) .

• Background Reference 04:

  Salzer, U., et al., Biochim. Biophys. Acta 1446 (3) :365-370 (1999) .

• Other Product Names:

  RuvB-like 2, 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, ECP-51, INO80 complex subunit J, Repressing pontin 52, Reptin 52, TIP49b, TIP60-associated protein 54-beta, TAP54-beta, RUVBL2, INO80J, TIP48, TIP49B

• Tested Applications:

  WB

• Protein ID:

  28201890

• Physical Properties:

  Liquid