RUVBL2 Antibody

CAT: 0223-27-570Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-570Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RuvB-Like 2 (48-kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
NCBI Gene ID
10856
Swiss Prot
Q9Y230
Accession Number
NP_006657
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUVBL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Homeostasis
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RUVBL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
RUVBL2 antibody can be used for detection of RUVBL2 by ELISA at 1:312500. RUVBL2 antibody can be used for detection of RUVBL2 by western blot at 2.0-4.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RUVBL2
NCBI Official Name
RuvB-like AAA ATPase 2
NCBI Organism
Homo sapiens
Background Reference 01
Bauer, A., et al., (2000) EMBO J.19 (22), 6121-6130.
Other Product Names
RUVBL2, RVB2, TIH2, ECP51, TIP48, CGI-46, INO80J, REPTIN, TIP49B
Tested Applications
ELISA, WB, IHC
Protein ID
5730023
Physical Properties
Liquid

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