SIRPB2 Antibody

• Background:

  Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.

• NCBI Gene ID:

  284759

• Swiss Prot:

  Q5JXA9

• Accession Number:

  Q5JXA9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-255 amino acids from the C-terminal region of human SIRPB2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SIRPB2

• NCBI Official Name:

  Signal-regulatory protein beta-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nyati, M.K., et al. Cancer Res. 66 (24) :11554-11559 (2006)

• Background Reference 02:

  Van den Berg, T.K., et al. J. Immunol. 175 (12) :7788-7789 (2005)

• Background Reference 03:

  Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99 (19) :12257-12262 (2002)

• Other Product Names:

  Signal-regulatory protein beta-2, SIRP-beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein, SIRPB2, PTPN1L, PTPNS1L3

• Tested Applications:

  WB

• Protein ID:

  74762205

• Physical Properties:

  Liquid