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SIRT2 Antibody

CAT: 0223-27-575Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-575Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SIRT2 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT2 is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.
NCBI Gene ID
22933
Swiss Prot
Q8IXJ6
Accession Number
NP_085096
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIRT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIRT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
40 kDa, 43 kDa
Applications Notes
SIRT2 antibody can be used for detection of SIRT2 by ELISA at 1:312500. SIRT2 antibody can be used for detection of SIRT2 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SIRT2
NCBI Official Name
Sirtuin 2
NCBI Organism
Homo sapiens
Background Reference 01
Borra, M.T., et al., (2004) Biochemistry 43 (30), 9877-9887.
Other Product Names
SIRT2, SIR2, SIR2L, SIR2L2
Tested Applications
ELISA, WB
Protein ID
13775602
Physical Properties
Liquid

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