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XYLT2 Antibody

CAT: 0223-60-352Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-352Size:400 µL
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Background
The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.
NCBI Gene ID
64132
Swiss Prot
Q9H1B5
Accession Number
Q9H1B5
Host
Rabbit
Reactivity
Mouse
Immunogen
This XYLT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human XYLT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
97 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
XYLT2
NCBI Official Name
Xylosyltransferase 2
NCBI Organism
Homo sapiens
Background Reference 01
Condac, E., et al. Glycobiology 19 (8) :829-833 (2009)
Background Reference 02
Casanova, J.C., et al. Biochem. Biophys. Res. Commun. 383 (1) :4-10 (2009)
Background Reference 03
Ponighaus, C., et al. Am. J. Hypertens. 22 (4) :432-436 (2009)
Background Reference 04
Ambrosius, M., et al. Clin. Biochem. 42 (1-2), 1-4 (2009) :
Other Product Names
Xylosyltransferase 2, Peptide O-xylosyltransferase 1, Xylosyltransferase II, XT-II, XylT-II, XYLT2, XT2
Tested Applications
WB
Protein ID
126302616
Physical Properties
Liquid