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XYLT1 Antibody

CAT: 0223-56-641Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-641Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.
NCBI Gene ID
64131
Swiss Prot
Q86Y38
Accession Number
Q86Y38
Host
Rabbit
Reactivity
Human
Immunogen
This XYLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the N-terminal region of human XYLT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Symbol
XYLT1
NCBI Official Name
Xylosyltransferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Muller, B., et al. J. Biol. Chem. 284 (45) :30775-30782 (2009)
Background Reference 03
Ponighaus, C., et al. Am. J. Hypertens. 22 (4) :432-436 (2009)
Background Reference 04
Ambrosius, M., et al. Clin. Biochem. 42 (1-2), 1-4 (2009) :
Other Product Names
Xylosyltransferase 1, Peptide O-xylosyltransferase 1, Xylosyltransferase I, XT-I, XylT-I, XYLT1, XT1
Tested Applications
WB, Flow
Protein ID
71164803
Physical Properties
Liquid

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