MOCS1 Antibody

• Background:

  Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.

• NCBI Gene ID:

  4337

• Swiss Prot:

  Q9NZB8

• Accession Number:

  Q9NZB8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MOCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human MOCS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  70 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MOCS1

• NCBI Official Name:

  Molybdenum cofactor biosynthesis protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sass, J.O., et al. Brain Dev. (2009) In press :

• Background Reference 02:

  Arenas, M., et al. J. Inherit. Metab. Dis. 32 (4) :560-569 (2009)

• Background Reference 03:

  Ichida, K., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1087-1091 (2006) :

• Background Reference 04:

  Macaya, A., et al. Neuropediatrics 36 (6) :389-394 (2005)

• Other Product Names:

  Molybdenum cofactor biosynthesis protein 1, Cell migration-inducing gene 11 protein, Molybdenum cofactor synthesis-step 1 protein A-B, Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein A, Cyclic pyranopterin monophosphate synthase accessory protein, Molybdenum cofactor biosynthesis protein C, MOCS1

• Tested Applications:

  WB

• Protein ID:

  30913216

• Physical Properties:

  Liquid