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MOCS1 Antibody

CAT: 0223-60-344Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-344Size:400 µL
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Background
Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.
NCBI Gene ID
4337
Swiss Prot
Q9NZB8
Accession Number
Q9NZB8
Host
Rabbit
Reactivity
Human
Immunogen
This MOCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human MOCS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MOCS1
NCBI Official Name
Molybdenum cofactor biosynthesis protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Sass, J.O., et al. Brain Dev. (2009) In press :
Background Reference 02
Arenas, M., et al. J. Inherit. Metab. Dis. 32 (4) :560-569 (2009)
Background Reference 03
Ichida, K., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1087-1091 (2006) :
Background Reference 04
Macaya, A., et al. Neuropediatrics 36 (6) :389-394 (2005)
Other Product Names
Molybdenum cofactor biosynthesis protein 1, Cell migration-inducing gene 11 protein, Molybdenum cofactor synthesis-step 1 protein A-B, Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein A, Cyclic pyranopterin monophosphate synthase accessory protein, Molybdenum cofactor biosynthesis protein C, MOCS1
Tested Applications
WB
Protein ID
30913216
Physical Properties
Liquid

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