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MOCS2 Antibody

CAT: 0223-58-378Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-378Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.
NCBI Gene ID
4338
Swiss Prot
O96007
Accession Number
O96007
Host
Rabbit
Reactivity
Human
Immunogen
This MOCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human MOCS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MOCS2
NCBI Official Name
Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}
NCBI Organism
Homo sapiens
Background Reference 01
Per, H., et al. Brain Dev. 29 (6) :365-368 (2007)
Background Reference 02
Hahnewald, R., et al. Mol. Genet. Metab. 89 (3) :210-213 (2006)
Background Reference 03
Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)
Background Reference 04
Leimkuhler, S., et al. Hum. Genet. 117 (6) :565-570 (2005)
Other Product Names
Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}, 28112 {ECO:0000255|HAMAP-Rule:MF_03052}, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdenum cofactor synthesis protein 2B {ECO:0000255|HAMAP-Rule:MF_03052}, MOCS2B {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdopterin-synthase large subunit, MPT synthase large subunit, MOCS2 {ECO:0000255|HAMAP-Rule:MF_03052}, MCBPE, MOCO1
Tested Applications
WB
Physical Properties
Liquid

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