MOCS2 Antibody

• Background:

  Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.

• NCBI Gene ID:

  4338

• Swiss Prot:

  O96007

• Accession Number:

  O96007

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MOCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human MOCS2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  21 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MOCS2

• NCBI Official Name:

  Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Per, H., et al. Brain Dev. 29 (6) :365-368 (2007)

• Background Reference 02:

  Hahnewald, R., et al. Mol. Genet. Metab. 89 (3) :210-213 (2006)

• Background Reference 03:

  Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

• Background Reference 04:

  Leimkuhler, S., et al. Hum. Genet. 117 (6) :565-570 (2005)

• Other Product Names:

  Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}, 28112 {ECO:0000255|HAMAP-Rule:MF_03052}, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdenum cofactor synthesis protein 2B {ECO:0000255|HAMAP-Rule:MF_03052}, MOCS2B {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdopterin-synthase large subunit, MPT synthase large subunit, MOCS2 {ECO:0000255|HAMAP-Rule:MF_03052}, MCBPE, MOCO1

• Tested Applications:

  WB

• Physical Properties:

  Liquid