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PMM2 Antibody

CAT: 0223-60-261Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-261Size:400 µL
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Background
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq].
NCBI Gene ID
5373
Swiss Prot
O15305
Accession Number
O15305
Host
Rabbit
Reactivity
Human
Immunogen
This PMM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human PMM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Monkey, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PMM2
NCBI Official Name
Phosphomannomutase 2
NCBI Organism
Homo sapiens
Background Reference 01
Vega, A.I., et al. Hum. Mutat. 30 (5) :795-803 (2009)
Background Reference 02
Coman, D., et al. Am. J. Med. Genet.146 (3) :389-392 (2008)
Background Reference 03
Vermeer, S., et al. J. Neurol. 254 (10) :1356-1358 (2007)
Background Reference 04
Coman, D., et al.Clin Neurosci 14 (7) :668-672 (2007)
Other Product Names
Phosphomannomutase 2, PMM 2, PMM2
Tested Applications
WB
Physical Properties
Liquid

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