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CHST5 Antibody

CAT: 0223-60-215Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-215Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The carbohydrates of glycoconjugates are highly diverse structures with variation in monosaccharide composition, glycosidic linkage positions, and branching of chains. Further diversity is added by the covalent addition of sulfate moieties to particular hydroxyl groups and amino groups of saccharides. The sulfate modifications of glycoproteins can be extensive in amount and frequently occur at high density. They can have a profound effect on the physiochemical properties of the glycoconjugates, at least in part through the addition of negative charge. Carbohydrate sulfation plays a critical role in many biologic processes. CHST5 belongs to the GST family of sulfotransferases, which also includes CHST1 (MIM 603797), CHST2 (MIM 603798), CHST3 (MIM 603799), and LSST. These enzymes are 6-O-sulfotransferases, which add sulfate to C6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) (Lee et al., 1999 [PubMed 10491328]) .
NCBI Gene ID
23563
Swiss Prot
Q9GZS9
Accession Number
Q9GZS9
Host
Rabbit
Reactivity
Human
Immunogen
This CHST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human CHST5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CHST5
NCBI Official Name
Carbohydrate sulfotransferase 5
NCBI Organism
Homo sapiens
Background Reference 01
Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)
Background Reference 02
Dastani, Z., et al. Eur. J. Hum. Genet. 18 (3) :342-347 (2010)
Background Reference 03
Saito, A., et al. J. Hum. Genet. 54 (6) :317-323 (2009)
Background Reference 04
Kitayama, K., et al. J. Biol. Chem. 282 (41) :30085-30096 (2007)
Other Product Names
Carbohydrate sulfotransferase 5, 282-, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha, GST4-alpha, Intestinal N-acetylglucosamine-6-O-sulfotransferase, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, hIGn6ST, N-acetylglucosamine 6-O-sulfotransferase 3, GlcNAc6ST-3, Gn6st-3, CHST5
Tested Applications
WB
Protein ID
239938912
Physical Properties
Liquid

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